منابع مشابه
Targeted Therapy for Biliary Tract Cancer
It is necessary to establish effective chemotherapy to improve the survival of patients with biliary tract cancer, because most of these patients are unsuitable candidates for surgery, and even patients undergoing curative surgery often have recurrence. Recently, the combination of cisplatin plus gemcitabine was reported to show survival benefits over gemcitabine alone in randomized clinical tr...
متن کاملMolecular Targeted Therapy for Biliary Tract Cancer- A Future Perspective
Bile duct cancer is subdivided according to the anatomic location of origin into intrahepatic and extrahepatic cholangiocarcinoma, gallbladder cancer, or ampulla of Vater cancer. While biliary tract cancer is uncommon in Western countries, the incidence is relatively high in Asia, including Japan, and Latin America. However, in biliary tract cancers, the incidence of intrahepatic cholangiocarci...
متن کاملTargeted Therapy in Biliary Tract Cancers
OPINION STATEMENT A paradigm shift towards molecular-based, personalized cancer therapeutics has occurred in recent years and a number of targeted drugs have emerged. Various targeted therapies like erlotinib, trastuzumab, and cetuximab have been approved in lung, breast, and colon cancers, respectively. Numerous clinical trials involving targeted drugs in biliary tract cancers are currently in...
متن کاملTargeted cancer therapy: review article
Cancer is one of the most dangerous health problems of today modern societies which has an increasing rate especially in developing countries. There are many diverse ongoing treatment attempts trying to defeat cancer. Despite that, scientists have been unable to find a permanent cure for this disease. In many cases although there is a successful first response in patients, cancer cells are fina...
متن کاملGenomic Alterations in Biliary Tract Cancer Using Targeted Sequencing1
BACKGROUND Biliary tract cancers (BTCs) are rare and heterogeneous group of tumors classified anatomically into intrahepatic and extrahepatic bile ducts and gallbladder adenocarcinomas. Patient-derived tumor cell (PDC) models with genome analysis can be a valuable platform to develop a method to overcome the clinical barrier on BTCs. MATERIAL AND METHODS Between January 2012 and June 2015, 40...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Lancet Oncology
سال: 2010
ISSN: 1470-2045
DOI: 10.1016/s1470-2045(09)70370-5